基本信息
|
姓名:
|
严建兵
|
出生年月:
|
1976.05
|
|
性别:
|
男
|
硕/博导:
|
博导
|
|
民族:
|
汉
|
开设课程:
|
遗传学、遗传学进展、学术道德规范教育等
|
|
职称:
|
教授
|
研究方向:
|
主要从事玉米基因组学和分子育种研究 |
|
学位:
|
博士
|
联系方式
办公电话:027-87280110
电子邮件:yjianbing@mail.hzau.edu.cn
实验室主页:www.maizego.org
教育经历
1995.09-1999.06 华中农业大学 生命科学技术学院 生物技术专业 理学学士学位
1998.09-2003.06 华中农业大学 生命科学技术学院 遗传学专业 理学博士学位
科研与学术工作经历
2003.12-2005.09 中国农业大学讲师
2005.10-2009.07 中国农业大学副教授
2006.10-2008.09 国际玉米小麦改良中心和康奈尔大学博士后
2008.10-2009.08 国际玉米小麦改良中心副科学家
2009.09-2011.03 国际玉米小麦改良中心科学家
2010.09-至今华中农业大学(含6个月过渡期)教授
代表性研究成果
论文
1) Peng Y#, Xiong D#, Zhao L, Ouyang W, Wang S, Sun J, Zhang Q, Guan P, Xie L, Li W, Li G, Yan J*, Li X* (2019) Chromatin interaction maps reveal genetic regulation for quantitative traits in maize. Nat Commun, 10(1):2632
2) Yan J*, Tan BC (2019) Maize biology: From functional genomics to breeding application. J Integr Plant Biol, 2019, 61(6):654-657
3) Zhan W, Liu J, Pan Q, Wang H, Yan S, Li K, Deng M, Li W, Liu N, Kong Q, Fernie AR, Yan J* (2019) An allele of ZmPORB2 encoding a protochlorophyllide oxidoreductase promotes tocopherol accumulation in both leaves and kernels of maize. Plant J, DOI: 10.1111/tpj.14432
4) Yang N#, Liu J#, Gao Q#, Gui S, Chen L, Yang L, Huang J, Deng T, Luo J, He L, Wang Y, Xu P, Peng Y, Shi Z, Lan L, Ma Z, Yang X, Zhang Q, Bai M, Li S, Li W, Liu L, Jackson D, Yan J* (2019) Genome assembly of a tropical maize inbred line provides insights into structural variation and crop improvement. Nat Genet, 51(6):1052-1059
5) Fernie AR*, Yan J* (2019) De Novo Domestication: An Alternative Route toward New Crops for the Future. Mol Plant, 12(5):615-631
6) Li K#, Wen W#, Alseekh S, Yang X, Guo H, Li W, Wang L, Pan Q, Zhan W, Liu J, Li Y, Wu X, Brotman Y, Willmitzer L, Li J*, Fernie AR*, Yan J* (2019) Large-scale metabolite quantitative trait locus analysis provides new insights for high-quality maize improvement. Plant J, 99(2):216-230
7) Li X#, Chen L#, Zhang Q, Sun Y, Li Q*, Yan J* (2019) BRIF-Seq: Bisulfite-Converted Randomly Integrated Fragments Sequencing at the Single-Cell Level. Mol Plant, 12(3):438-446
8) Luo C#, Li X*#, Zhang Q, Yan J*(2019)Single gametophyte sequencing reveals that crossover events differ between sexes in maize. Nat Commun, 10(1):785
9) Wang H, Xu S, Fan Y, Liu N, Zhan W, Liu H, Xiao Y, Li K, Pan Q, Li W, Deng M, Liu J, Jin M, Yang X, Li J, Li Q*,Yan J* (2018) Beyond pathways: genetic dissection of tocopherol content in maize kernels by combining linkage and association analyses. Plant Biotechnol J,16(8):1464-1475
10) Wen W#, Jin M#, Li K, Liu H, Xiao Y, Zhao M, Alseekh S, Li W, de Abreu E Lima F, Brotman Y, Willmitzer L, Fernie AR*, Yan J*(2018) An Integrated Multi-layered Analysis of the Metabolic Networks of Different Tissues Uncovers Key Genetic Components of Primary Metabolism in Maize. Plant J, 93(6), 1116–1128
11) Liu H*, Yan J*(2018) Crop genome-wide association study: A harvest of biological relevance. Plant J, 97(1):8-18
12) Ma H#, Li G#, Würschum T, Zhang Y, Zheng D, Yang X, Li J, Liu W, Yan J*, Chen S* (2018) Genome-Wide Association Study of Haploid Male Fertility in Maize (Zea Mays L.). Front Plant Sci 9: 974
13) Jin M, Liu X*, Jia W, Liu H, Li W, Peng Y, Du Y, Wang Y, Yin Y, Zhang X, Liu Q, Deng M, Li N, Cui C, Hao D, Yan J* (2018) ZmCOL3, a CCT gene represses flowering in maize by interfering circadian clock and activating expression of ZmCCT. J Integr Plant Biol, 60(6):465-480
14) Li X#, Meng D#, Chen S, Luo H, Zhang Q, Jin W*, Yan J*(2017) Single nucleus sequencing reveals spermatid chromosome fragmentation as a possible cause of maize haploid induction. Nat Commun, 8(1):991
15) Yang N#, Xu XW#, Wang RR, Peng WL, Cai L, Song JM, Li W1 Luo X, Niu L, Wang Y, Jin M, Chen L, Luo J, Deng M, Wang L, Pan Q, Liu F, Jackson D, Yang X, Chen L*, Yan J* (2017) Contributions of Zea mays subspecies mexicana haplotypes to modern maize. Nat Commun, 8(1):1874
16) Liu H*, Yan J*(2017) RICE DOMESTICATION: An imperfect African solution. Nat Plants, 3(6)
17) Liu C#, Li X#, Meng D#, Zhong Y, Chen C, Dong X, Xu X, Chen B, Li W, Li L, Tian X, Zhao H, Song W, Luo H, Zhang Q, Lai J, Jin W*,Yan J*, Chen S* (2017) A 4-bp Insertion at ZmPLA1 Encoding a Putative Phospholipase A Generates Haploid Induction in Maize. Mol Plant, 10(3):520-522
18) Xiao Y#, Liu H#, Wu L#, Warburton M, Yan J*(2017) Genome-wide association studies in maize: praise and stargaze. Mol Plant, 10(3):359-374
19) Deng M, Li D, Luo J, Xiao Y, Liu H, Pan Q, Zhang X, Jin M, Zhao M, Yan J* (2017) The genetic architecture of amino acids dissection by association and linkage analysis in maize. Plant Biotechnol J,15(10):1250-1263
20) Pan Q, Xu Y, Li K, Peng Y, Zhan W, Li W, Li L*, Yan J*(2017) The Genetic Basis of Plant Architecture in 10 Maize Recombinant Inbred Line Populations. Plant Physiol, 175(2):858-873
21) Liu J, Huang J, Guo H, Lan L, Wang H, Xu Y, Yang X, Li W, Tong H, Xiao Y, Pan Q, Qiao F, Raihan MS, Liu HJ, Zhang X, Yang N, Wang X, Deng M, Jin M, Zhao L, Luo X, Zhou Y, Li X, Zhan W, Liu N, Wang H, Chen G, Li Q*, Yan J* (2017) The Conserved and Unique Genetic Architecture of Kernel Size and Weight in Maize and Rice. Plant Physiol, 175(2):774-785
22) Zhang X#, Huang C#, Wu D, Qiao F, Li W, Duan L, Wang K, Xiao Y, Chen G, Liu Q, Xiong L, Yang W*, Yan J*(2017) High-throughput phenotyping and QTL mapping reveals the genetic architecture of maize plant growth. Plant Physiol, 173(3):1554-1564
23) Liu H#, Luo X#, Niu L, Xiao Y, Chen L, Liu J, Wang X, Jin M, Li W, Zhang Q, Yan J*(2016)Distant eQTLs and non-coding sequences play critical roles in regulating gene expression and quantitative trait variation in maize. Mol Plant, 10(3):414-426
24) Xiao Y#, Tong H#, Yang X, Xu S, Pan Q, Qiao F, Raihan M, Luo Y, Liu H, Zhang X, Yang N, Wang X, Deng M, Jin M, Zhao L, Luo X, Zhou Y, Li X, Liu J, Zhan Wei, Liu N, Wang H, Chen G, Cai Y, Xu G, Wang W, Zheng D, Yan J*(2016) Genome-wide dissection of the maize ear genetic architecture by using multiple populations. New Phytol, 210(3):1095-106
25) Pan Q#, Li L#, Yang X, Tong H, Xu S, Li Z, Li W, Muehlbauer G, Li J, Yan J* (2016) Genome-wide recombination dynamics are associated with phenotypic variation in maize. New Phytol, 210(3):1083-94
26) Jin M#, Liu H#, He C#, Fu J ,Xiao Y, Wang Y, Xie W, Yan J*(2016) Maize pan-transcriptome provides novel insights into genome complexity and quantitative trait variation. Sci Rep, 6:18936
27) Li X, Li L, Yan J* (2015) Dissecting meiotic recombination based on tetrad analysis by single microspore sequencing in maize. Nat Commun, 6: 6648
28) Wen W, Li K, Alseekh S, Omranian N, Zhao L, Zhou Y, Xiao Y, Jin M, Yang N, Liu H, Florian A, Li W, Pan Q, Nikoloski Z, Yan J*, Fernie A* (2015) Genetic Determinants of the Network of Primary Metabolism and Their Relationships to Plant Performance in a Maize Recombinant Inbred Line Population. Plant Cell, 27: 1839–1856
29) Liu H, Wang X, Warburton M, Wen W, Jin M, Deng M, Liu J, Tong H, Pan Q, Yang X, Yan J* (2015) Genomic, transcriptomic and phenomic variation reveals the complex adaptation of modern maize breeding. Mol Plant, 8(6): 871-884
30) Liu J, Deng M, Guo H, Raihan D, Luo J, Xu Y, Dong X, Yan J* (2015) Maize orthologs of rice GS5 and their trans-regulator are associated with kernel development. J Integr Plant Biol, 57(11):943-953
31) Ding J, Ali F, Chen G, Li H, Mahuku G, Yang N, Narro L, Magorokosho C, Makumbi D, Yan J* (2015) Genome-wide association mapping reveals novel sources of resistance to northern corn leaf blight in maize. BMC Plant Biol, 15:206
32) Guo T, Yang N, Tong H, Pang Q, Yang X, Tang J, Wang J, Li J, Yan J* (2014) Genetic basis of grain yield heterosis in an “immortalized F2s” maize population. Theor Appl Genet,127: 2149-2158
33) Wen W, Li D, Li X, Gao Y, Li W, Li H, Liu J, Liu H, Chen W, Luo J*, Yan J* (2014) Metabolome-based genome-wide association study of maize kernel leads to novel biochemical insights. Nat Commun,5:3438
34) Yang N, Lu Y, Yang X, Huang J, Zhou Y, Ali F, Wen W, Liu J, Li J, Yan J* (2014) Genome wide association studies using a new nonparametric model reveal the genetic architecture of 17 agronomic traits in an enlarged maize association panel. PLoS Genet, 10(9):e1004573
35) Li H, Peng Z, Yang X, Wang W, Fu J, Wang J, Han Y, Chai Y, Guo T, Yang N, Liu J, Warburton ML, Cheng Y, Hao X, Zhang P, Zhao J, Liu Y, Wang G*, Li J*, Yan J* (2013) Genome-wide association study dissects the genetic architecture of oil biosynthesis in maize kernels. Nat Genet, 45: 43-50
36) Fu J, Cheng Y, Linghu J, Yang X, Kang L, Zhang Z, Zhang J, He C, Du X, Peng Z, Wang B, Zhai L, Dai C, Xu J, Wang W, Li X, Zheng J, Chen L, Luo L, Liu J, Qian X, Yan J*, Wang J*, Wang G* (2013) RNA sequencing reveals the complex regulatory network in the maize kernel. Nat Commun,4:2832
37) Yang Q, Li Z, Li W, Ku L, Ye J, Li K, Yang N, Li Y, Zhong T, Li J, Chen Y*, Yan J*, Yang X*, Xu M* (2013) CACTA-like transposable element in ZmCCT attenuated photoperiod sensitivity and accelerated the postdomestication spread of maize. Proc Natl Acad Sci USA,110(42): 16969-16974
38) Xue Y, Warburton ML, Sawkins M, Zhang X, Setter T, Xu Y, Grudloyma P, Gethi J, Ribaut JM, Li W, Zhang X, Zheng Y, Yan J* (2013) Genome-wide association analysis for nine agronomic traits in maize under well-watered and water-stressed conditions. Theor Appl Genet, 126(10): 2587-2596
39) Fu Z, Chai Y, Zhou Y, Yang X, Warburton ML, Xu S, Cai Y, Zhang D, Li J, Yan J* (2013) Natural variation in the sequence of PSY1 and frequency of favorable polymorphisms among tropical and temperate maize germplasm. Theor Appl Genet,126(4):923-935
40) Xu S, Zhang D, Cai Y, Zhou Y, Shah T, Ali F, Li Q, Li Z, Wang W, Li J, Yang X, Yan J* (2012) Dissecting tocopherols content in maize (Zea mays L.), using two segregating populations and high-density single nucleotide polymorphism markers. BMC Plant Biol, 12:201
41) Yang X, Gao S, Xu S, Zhang Z, Prasanna BM, Li L, Li J, Yan J* (2011) Characterization of a global germplasm collection and its potential utilization for analysis of complex quantitative traits in maize. Mol Breeding, 28 (4): 511-526
42) Yan J#, Kandianis C#, Harjes C, Bai L, Kim E, Yang X, Skinner D, Fu Z, Mitchell S, Li Q, Fernandez M, Zaharieva M, Babu R, Fu Y, Palacios N, Li J, Dellapenna D, Brutnell T, Buckler ES, Warburton ML*, Rocheford T* (2010) Rare genetic variation at Zea mays crtRB1 increases β-carotene in maize grain. Nat Genet, 42 (4): 322-327 (# co-first author)
授权专利
1.严建兵、杨小红、李建生、李慧,一种玉米油份含量相关基因的分子标记的应用,2012.11.09,中国,201210444716111(专利号),CN102925457A(专利公布号)
2.严建兵、杨小红、李建生、李慧,一种与玉米GPAT基因连锁的SNP位点及其应用,2012.11.09,中国,2012104446811(专利号),CN102899324A(专利公布号)
3.严建兵、杨小红、李建生、李慧,一种玉米油份含量相关的SNP位点及其应用,2012.11.09,中国,2012104446737(专利号),CN102994496A(专利公布号)
4.严建兵、杨小红、李建生、李慧,玉米油份含量相关的衣被蛋白复合体(COPII)基因位点及应用,2012.11.09,中国,2012104447176(专利号),CN102978203A(专利公布号)
5.严建兵、杨小红、李建生、李慧,一种玉米油份含量相关的LACS基因位点及其应用,2012.11.09,中国,2012104446826(专利号),CN102911949A(专利公布号)
6.李建生、高玉峰、严建兵、邢安琪、张卫平、郑艳萍、杨小红,与玉米株高性状相关的SNP位点,2012.03.14,中国,2011103332626(专利号),CN102373278A(专利公布号)
7.李建生、严建兵、李林、李慧、郑德波、张义荣、郑艳萍,参与软脂酸合成的蛋白、基因和功能片段以及它们的应用,2010.09.16,中国,201010285616X(专利号),CN101948517A(专利公布号)
8.李建生、杜何为、刘志鹏、惠国强、严建兵、张义荣、郑艳萍,玉米单倍体胚芽鞘节组织培养的方法及其专用培养基,2010.04.01,中国,2010101397320(专利号),CN101805721A(专利公布号)
获得奖励
2018年荣获第七届中国侨界贡献奖二等奖
2016年入选科技部创新人才推进计划“中青年科技创新领军人才”;获第14届中国青年科技奖;
2015年入选农业部“农业科研杰出人才”,带领的玉米团队入选农业部“创新团队”和湖北省自然基金委创新团队;获国家杰出青年科学基金
2013年教育部技术发明奖一等奖(第二完成人)
2012年获国家自然科学基金委优秀青年基金
2011年入选教育部“新世纪人才计划”、荣获“杜邦青年教授奖”
2010年荣获日本“国际青年农业科学家奖”