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郭亮
发布时间:2017-02-22

基本信息

  姓名: 郭亮 出生年月: 1981.12
  性别: 硕/博导: 博导
  民族: 开设课程: 普通遗传学(本科)和植物生物技术(研究生英文课程)
  职称: 教授 研究方向: 油菜脂质代谢和抗逆性的遗传基础和分子机制
  学位: 理学博士

联系方式
 办公电话:027-87286881
 电子邮件:guoliang@mail.hzau.edu.cn

个人简介
华中农业大学教授、博士生导师,“千人计划”青年人才,作物遗传改良国家重点实验室固定研究人员,油菜遗传改良团队成员。2001-2006年先后获四川大学本科学位(生物技术)和硕士学位(植物学),2006-2011年获美国密苏里大学圣路易斯校区细胞与分子生物学博士学位,2012-2014年在美国Donald Danforth Plant Science Center从事博士后研究。

课题组围绕油菜籽含油量和油菜抗非生物逆境,主要开展以下研究:

1. 油菜脂质代谢与功能:1) 油菜油脂合成的遗传基础和分子机制,发掘调控油菜籽油分积累的关键基因和代谢途径; 2) 磷脂、鞘脂和表面脂的合成与代谢途径,以及这些脂质参与调控油菜生长、发育和抗逆的分子机制研究; 3) 油菜脂质组分析方法的建立和应用,开展全面的脂质组学研究,致力于建立高通量、高灵敏度和系统性的脂质组分析方法;

2. 油菜抗旱、耐盐和抗冻等性状的遗传基础和分子机制:包括油菜抗逆种质资源的筛选、评价和利用,通过全基因组关联分析等手段解析调控油菜抗逆的分子机制;

3. 代谢组分析及其在油菜代谢和抗逆中的应用:通过代谢组分析,筛选和鉴定油菜逆境响应过程中的代谢标记物以及相关代谢途径和关键基因。

课题组利用丰富的油菜种质资源,结合基因组、代谢组和表型组等手段全面解析油菜脂质代谢与抗非生物逆境的遗传基础和分子机制,实现油菜优异种质资源创新与利用→优异基因挖掘→优异基因功能解析→优异基因利用,为培育高含油量和抗逆强的油菜品种打下基础,将一批实用的基因应用到油菜遗传改良中。

欢迎热爱农业科学研究的优秀学生报考本题组研究生!
本课题组2016年招收博士后1-2名,请将个人材料发至:guoliang@mail.hzau.edu.cn

科研项目
1.“七大物育种”小麦等作物功能基因组研究与应用,项目骨干 (2016-2020)
2.“千人计划”青年人才项目,主持 (2016-2018)
3. 国家自然科学基金面上项目:植物鞘脂介导的信号传导研究,主持 (2016-2019)
4. 华中农业大学自主科技创新基金:基于脂质组分析解析油菜种子高含油量的分子机制,主持 (2015-2020))
5. 华中农业大学引进人才科研启动项目:植物脂质代谢与功能研究,主持 (2015-2019)
6. 作物遗传改良国家重点实验室科研启动项目:植物脂质组分析方法的建立与应用,主持 (2015-2019)

发明专利及获奖情况
第十二批“千人计划”青年人才 (2016)
Raju Mehra Awards (University of Missouri-St Louis, 2011)

发表的论文及著作
1. Fang Wei, Brian Fanella, Liang Guo* and Xuemin Wang* (2016) Membrane glycerolipidome of soybean root hairs and its response to nitrogen and phosphate availability. Scientific Reports 6: 36172
2. Yueyun Hong*, Jian Zhao*, Liang Guo, Sang-Chul Kim, Xianjun Deng, Geliang Wang, Gaoyang Zhang, Maoyin Li, and Xuemin Wang* (2016) Plant Phospholipases D and C and Their Diverse Functions in Stress Responses. Progress in Lipid Research 62: 55-74
3. Shaoping Lu*, Shuaibing Yao, Geliang Wang, Liang Guo, Yongming Zhou, Yueyun Hong and Xuemin Wang* (2016) Phospholipase Dε enhances Braasca napus growth and seed production in response to nitrogen availability. Plant Biotechnol J 14:926-937
4. Jian Wu, Qing Zhao, Qingyong Yang, Han Liu, Qingyuan Li, Xinqi Yi, Yan Cheng, Liang Guo, Chuchuan Fan, Yongming Zhou* (2016) Comparative transcriptomic analysis uncovers the complex genetic network for resistance to Sclerotinia sclerotiorum in Brassica napus. Scientific Reports 6:19007
5. Liang Guo, Fangfang Ma, Fang Wei, Brian Fanella, Doug K. Allen and Xuemin Wang* (2014) Cytosolic Glyceraldehyde-3-Phosphate Dehydrogenase Affects Arabidopsis Cellular Metabolism and Promotes Seed Oil Accumulation. Plant Cell 26:3023-3035
6. Xuemin Wang, Liang Guo, Geliang Wang, Maoyin Li (2014) PLD: Phospholipase Ds in Plant Signaling, Phospholipases in Plant Signaling, Springer: 3-26
7. Hongyan Yao, Geliang Wang, Liang Guo and Xuemin Wang* (2013) Phosphatidic Acid Interacts with WEREWOLF MYB and Regulates Its Nuclear Localization and Function in Arabidopsis. Plant Cell 25:5030-5042
8. Sang-Chul Kim, Liang Guo and Xuemin Wang* (2013) Phosphatidic Acid Binds to Cytosolic Glyceraldehyde-3-Phosphase Dehydrogenase and Promotes Its Cleavage in Arabidopsis. J Biol Chem 288:11834-11844
9. Liang Guo, Shivakumar P. Devaiah, Rama Narasimhan, Xiangqing Pan, Yanyan Zhang, Wenhua Zhang and Xuemin Wang* (2012) Cytosolic glyceraldehyde-3-phosphate dehydrogenases interact with phospholipase Dδ to transduce hydrogen peroxide signals in stress response in Arabidopsis. Plant Cell 24:2200-2212
10. Liang Guo, Girish Mishra, Jonathan E. Markham, Maoyin Li, Amanda Tawfall, Ruth Welti and Xuemin Wang* (2012) Connections between sphingosine kinase and phospholipase D in the abscisic acid signaling pathway in Arabidopsis. J Biol Chem 287:8286-8296
11. Liang Guo and Xuemin Wang* (2012) Crosstalk between phospholipase D and sphingosine kinase in plant stress signaling. Frontiers Plant Science 3:1-7
12. Liang Guo, Girish Mishra, Kyle Taylor, Xuemin Wang* (2011) Phosphatidic acid binds and stimulates Arabidopsis sphingosine kinases. J Biol Chem 286:13336-13345
13. Maoyin Li, Sung Chul Bahn, Liang Guo, William Musgrave, Howard Berg, Ruth Welti and Xuemin Wang* (2011) Patatin-related phospholipase pPLAIIIbeta-induced changes in lipid metabolism alter cellulose content and cell elongation in Arabidopsis. Plant Cell 23:1107-1123
14. Liang Guo, Renwei Qing, Wei He, Ying Xu, Lin Tang, Shenghua Wang and Fang Chen* (2008) Identification and characterization of a plastidial ω3-fatty acid desaturase gene from Jatrophacurcas.Chin J Appl Environ Biol 14:469-474
15. Bei Niu, Liang Guo, Mingming Zhao, Tong Luo, Rong Zhang, Fuli Zhang, Pei Hou, Ying Zhang, Ying Xu, Shenghua Wang and Fang Chen* (2008) Molecular cloning, characterization, and expression of an ω-3 fatty acid desaturase gene from Sapiumsebiferu. J BiosciBioeng106:375-380
16. 何玮,郭亮,王岚,杨威,唐琳,陈放* (2007) 麻疯树种质资源遗传多样性的 ISSR 分析. 应用与环境生物学报 13: 466-470
17. Meng Xiao, Qun Li, Li Wang, Liang Guo, Jing Li, Lin Tang, Ying Xu and Fang Chen* (2006) ISSR analysis of genetic diversity and genetic structure in natural populations of an endangered species Sinopodophyllumhexandrum (Royle) Ying from the Tibetan region of Sichuan province, China. J Integr Plant Biol 48:1140-1146
18. Qun Li, Meng Xiao, Liang Guo, Li Wang, Lin Tang, Ying Xu, Fang Yan and Fang Chen* (2005) Genetic diversity and genetic structure of an endangered species, Trillium tschonoskii. Biochemical Genetics 43:445-458
19. Meng Xiao, Qun Li, Liang Guo, Tong Luo, Wenxing He, Li Wang and Fang Chen* (2005) AFLP analysis on genetic diversity of an endangered species Sinopodophyllumhexandrum (Royle) Ying in the Tibetan region of Sichuan province, China. Biochemical Genetics 44:47-60
20. 李群,肖猛,郭亮,李静,段文霞,陈放*,王丽 (2005) 四川省珍稀濒危植物延龄草遗传多样性分析. 北京林业大学学报 27: 1-6
21. 戎芳,王胜华,赵小光,郭亮,魏琴,唐琳,徐莺,陈放* (2005) 麻疯树外植体愈伤组织中毒蛋白的 Westem-blot 鉴定. 四川大学学报: 自然科学版 42: 206-209

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