教授
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李林
发布时间:2017-02-22

                             

基本信息


姓名: 李林 出生年月: 1981.9

性别: 硕/博导: 博导

民族: 开设课程:

生物信息学、植物大数据技术、现代生物技术实践


职称: 教授 研究方向:

作物大数据与系统生物学


学位: 农学博士

 

联系方式
办公电话:027-87658491
电子邮件:hzaulilin@mail.hzau.edu.cn

 

个人简介

  李林,华中农业大学植物科学技术学院教授,博士生导师。中国农业大学本硕博连读,2010年获农学博士学位,同年去美国明尼苏达大学从事博士后及研究助理工作,于20167月正式回国建立实验室,主要利用生物大数据进行玉米株型建成分子机制研究。发表研究论文36篇,其中以第一或通讯作者在《Genome Biology》,《Molecular Plant》,《PLoS Genetics》,《New Phytologist》,《Plant Physiology》等国际主流期刊上发表研究论文篇。另外,以主要完成人身份获批发明专利一项。国家优秀青年基金项目获得者,湖北省高层次人才。主持并参与多项国家重要科研项目。

教育背景

          2005/9~2010/7,中国农业大学,农学与生物技术学院,遗传育种专业,博士

          2001/9~2005/7,中国农业大学,农学与生物技术学院,遗传育种专业,学士

工作经历

          2015/9~至今,华中农业大学植物科学技术学院教授,作物遗传改良国家重点实验室PI,玉米研究团队成员

          2013/6~2015/8,美国明尼苏达大学双城分校,研究助理

          2010/8~2013/6,美国明尼苏达大学双城分校,博士后

主要研究方向

 作物大数据及系统生物学

            
    本实验室将以小而精的模式,对每一个研究生都全力培养。除了实验室本身提供的课题外,本实验室也非常鼓励学生大胆创新,鼓励学生做与实验室方向完全不相关而自己感兴趣的课题。欢迎优秀学生报考本课题组研究生!

 

科研项目

8. 国家自然科学基金优秀青年基金项目-玉米株型建成分子机制,主持 2020-2022);

7. 国家自然科学基金重大研究计划集成项目-玉米株高基因sd7pin1subr2的调控网络解析,参与 2018-2020);

6. 国家自然科学基金面上项目-玉米籽粒大小基因Sem1 的分离克隆与分子机制研究,主持 (2018-2021)

5.“七大农作物育种”试点专项-主要农作物杂种优势形成与利用机理,项目骨干 (2016-2020)

4.“七大农作物育种”试点专项-主要农作物产量性状形成的分子基础,项目骨干 (2016-2020)

3. 华中农业大学自主科技创新基金-玉米与大刍草茎尖分生组织转录组比较研究,主持 (2016-2018)

2. 作物遗传改良国家重点实验室科研启动费-玉米近缘种大刍草野生资源开发与利用,主持  (2015-2020)

  1. 华中农业大学引进人才科研启动费-玉米及其近缘种大刍草株型建成分子机理剖析,主持  (2015-2020)。

 

发明专利及获奖情况

1. 李建生,严建兵,李林,李慧,郑德波,张义荣,郑艳萍. 参与软脂酸合成的蛋白、基因和功能片段以及它们的应用. 201207. 中国. ZL201010285616.X;

2. 获省部级以上奖励1项- “玉米重要营养品质优良基因发掘与分子育种应用”2013年获教育部科技发明一等奖,排名第七;

3. 湖北省楚天学者与海外高层次人才获得者。

 

发表的论文及著作

* - 通讯作者;# - 共同第一作者

2020

36, Luo, Z., Qian, J., Chen, S., and Li, L. * (2020). Dynamic patterns of circular and linear RNAs in maize hybrid and parental lines. Theoretical and Applied Genetics doi:10.1007/s00122-019-03489-9.

 

2019

35, Xu, J., Chen, G., Hermanson P.J., Xu, Q., Sun, C.S., Chen, W.Q., Kan, Q.X., Li, M.Q., Crisp, P.A., Yan, J.B., Li, L., Springer, N.M. and Li, Q. (2019). Population-level analysis reveals the widespread occurrence and phenotypic consequence of DNA methylation variation not tagged by genetic variation in maize. Genome Biology 20:243.

34, Knauer, S., Javelle, M., Li, L., Li, X., Ma, X., Wimalanathan, K., Kumari, S., Johnston, R., Leiboff, S., and Meeley, R. (2019). A high-resolution gene expression atlas links dedicated meristem genes to key architectural traits. Genome Research 29, 1962–1973.

33, Pan, Q., Wei, J., Guo, F., Huang, S., Gong, Y., Liu, H., Liu, J. *, and Li, L. * (2019). Trait ontology analysis based on association mapping studies bridges the gap between crop genomics and Phenomics. BMC Genomics 20, 443.

32, Zhang, H., Wang, X., Pan, Q., Li, P., Liu, Y., Lu, X., Zhong, W., Li, M., Han, L., and Li, J. … Li, L. * (2019a). QTG-Seq Accelerates QTL Fine Mapping through QTL Partitioning and Whole-Genome Sequencing of Bulked Segregant Samples. Molecular Plant 12, 426–437.

31, Zhang, L., Zhang, X., Wang, X., Xu, J., Wang, M., Li, L., Bai, G., Fang, H., Hu, S., and Li, J. (2019b). SEED CAROTENOID DEFICIENT Functions in Isoprenoid Biosynthesis via the Plastid MEP Pathway. Plant Physiology 179, 1723–1738.

30, Zhang, P., Fan, Y., Sun, X., Chen, L., Terzaghi, W., Bucher, E., Li, L., and Dai, M. (2019c). A large‐scale circular RNA profiling reveals universal molecular mechanisms responsive to drought stress in maize and Arabidopsis. The Plant Journal 98, 697–713.

29, Han, L., Mu, Z., Luo, Z., Pan, Q., and Li, L. * (2019a). New lncRNA annotation reveals extensive functional divergence of the transcriptome in maize. Journal of Integrative Plant Biology 61, 394–405.

28, Han, L., Li, L., Muehlbauer, G.J., Fowler, J.E., and Evans, M.M. (2019b). RNA Isolation and analysis of LncRNAs from gametophytes of maize. In Plant Long Non-Coding RNAs, (Humana Press, New York, NY), pp. 67–86.

27, Hemshrot, A., Poets, A.M., Tyagi, P., Lei, L., Carter, C.K., Hirsch, C.N., Li, L. , Brown-Guedira, G., Morrell, P.L., and Muehlbauer, G.J. (2019). Development of a multiparent population for genetic mapping and allele discovery in six-row barley. Genetics 213, 595–613.

26, Luo, Z., Han, L., Qian, J., and Li, L. * (2019b). Circular RNAs exhibit extensive intraspecific variation in maize. Planta 250, 69–78.

 

2018

25. Lu Chen#, Pei Zhang#, Yuan Fan#, Qiong Lu, Qing Li, Jianbing Yan, Gary J. Muehlbauer, Patrick S. Schnable, Mingqiu Dai and Lin Li*. Circular RNAs mediated by transposons are associated with transcriptomic and phenotypic variation in maize. New Phytologist 2018217 (3), 1292-1306.

 

2017

24. Qingchun Pan, Yuancheng Xu, Kun Li, Yong Peng, Wei Zhan, Wenqiang Li, Lin Li*, Jianbing Yan*. The Genetic Basis of Plant Architecture in 10 Maize Recombinant Inbred Line Populations. Plant Physiology, (October 2017), Vol. 175, pp. 858–873.


23. Martin Mascher, Heidrun Gundlach, Axel Himmelbach, Sebastian Beier,Sven O. Twardziok, Thomas Wicker, Volodymyr Radchuk,Christoph Dockter,Pete E. Hedley, Joanne Russell, Micha Bayer, Luke Ramsay, Hui Liu, Georg Haberer, Xiao-Qi Zhang, Qisen Zhang, Roberto A. Barrero, Lin Li, Stefan Taudien, Marco Groth, Marius Felder, Alex Hastie, Hana Šimková, Helena Staňková, Jan Vrána, Saki Chan, María Muñoz-Amatriaín, Rachid Ounit, Steve Wanamaker, Daniel Bolser, Christian Colmsee, Thomas Schmutzer, Lala Aliyeva-Schnorr, Stefano Grasso, Jaakko Tanskanen, Anna Chailyan, Dharanya Sampath, Darren Heavens, Leah Clissold, Sujie Cao, Brett Chapman, Fei Dai, Yong Han, Hua Li, Xuan Li, Chongyun Lin, John K. McCooke, Cong Tan, Penghao Wang, Songbo Wang, Shuya Yin, Gaofeng Zhou, Jesse A. Poland, Matthew I. Bellgard, Ljudmilla Borisjuk, Andreas Houben, Jaroslav Doležel, Sarah Ayling, Stefano Lonardi, Paul Kersey, Peter Langridge, Gary J. Muehlbauer, Matthew D. Clark, Mario Caccamo, Alan H. Schulman, Klaus F. X. Mayer, Matthias Platzer, Timothy J. Close, Uwe Scholz, Mats Hansson, Guoping Zhang, Ilka Braumann, Manuel Spannagl, Chengdao Li, Robbie Waugh & Nils Stein. A chromosome conformation capture ordered sequence of the barley genome. Nature 544, 427433 (27 April 2017) doi:10.1038/nature22043.

 

22. Martin Mascher, Sebastian Beier, Axel Himmelbach, Christian Colmsee, Xiao-Qi Zhang, Roberto Barrero, Qisen Zhang, Lin Li, Micha Bayer, Daniel Bolser, Stefan Taudien, Marco Groth, Marius Felder, Alex Hastie, Hana Simkova, Helena Stankova, Jan Vrana, Saki Chan, Maria Munoz-Amatriain, Rachid Ounit, Steve Wanamaker, Thomas Schmutzer, Lala Aliyeva-Schnorr, Stefano Grasso, Jaakko Tanskanen, Dharanya Sampath, Darren Heavens, Sujie Cao, Brett Chapman, Fei Dai, Yong Han, Xuan Li, John McCooke, Cong Tan, Songbo Wang, Shuya Yin, Gaofeng Zhou, Jesse Poland, Matthew Bellgard, Andreas Houben, Jaroslav Dolezel, Sarah Dyer, Stefano Lonardi, Peter Langridge, Gary Muehlbauer, Paul Kersey, Matthew Clark, Mario Caccamo, Alan Schulman, Matthias Platzer, Tim Close, Mats Hansson, Guoping Zhang, Ilka Braumann, Chengdao Li, Robbie Waugh, Uwe Scholz, Nils Stein, Chongyun Lin, and Hua Li. Construction of a map-based reference genome sequence for barley, Hordeum vulgare L. Scientific Data 4, 170044 (2017).

 

21. Qingchun Pan, Min Deng, Jianbing Yan & Lin Li*. Complexity of genetic mechanisms conferring nonuniformity of recombination in maize. Scientific Reports 7, Article number: 1205 (2017) doi:10.1038/s41598-017-01240-2.

2017年以前
20. Lin Li, Roman Briskine, Robert Schaefer, Patrick S. Schnable, Chad L. Myers, Lex E. Flagel, Nathan M. Springer, Gary J. Muehlbauer. Co-expression network analysis of duplicate genes in maize (Zea mays L.) reveals no subgenome bias. BMC Genomics, 2016 17:875.

 

19. Yadong Huang#, Lin Li#, Kevin P. Smith and Gary J. Muehlbauer. Differential transcriptomic responses to Fusarium graminearum infection in two barley quantitative trait loci associated with Fusarium head blight resistance. BMC Genomics, 2016, 17:387.

 

18. Qingchun Pan#, Lin Li#, Xiaohong Yang, Hao Tong, Shutu Xu, Zhigang Li, Weiya Li, Gary J. Muehlbauer, Jiansheng Li, Jianbing Yan. Genome-wide recombination dynamics are associated with phenotypic variation in maize. New Phytologist, 2016, 210:1083-1094.

 

17. Yingni Xiao, Shawn Thatcher, Min Wang, Tingting Wang, Mary Beatty, Gina ZastrowHayes, Lin Li, Jiansheng Li, Bailin Li, Xiaohong Yang: Transcriptome analysis of nearisogenic lines provides molecular insights into starch biosynthesis in maize kernel. Journal of integrative plant biology DOI: 10.1111/jipb.12455.

 

16. Xiang Li, Lin Li, Jianbing Yan: Dissecting Meiotic Recombination based on Tetrad Analysis by Single Microspore Sequencing in Maize. Nature communications 2015:6.

15. Lin Li, Steven R Eichten, Rena Shimizu, Katherine Petsch, Cheng-Ting Yeh, Wei Wu, Antony M Chettoor, Scott A Givan, Rex A Cole, John E Fowler, Matthew Ms Evans, Michael J Scanlon, Jianming Yu, Patrick S Schnable, Marja C Timmermans, Nathan M Springer, Gary J Muehlbauer: Genome-wide discovery and characterization of maize long non-coding RNAs. Genome biology 02/2014; 15(2):R40. Selected as an Editors' Choice by MaizeGDB, 07/14

 

14. Lin Li, Katherine Petsch, Rena Shimizu, Sanzhen Liu, Wayne Wenzhong Xu, Kai Ying, Jianming Yu, Michael J. Scanlon, Patrick S. Schnable, Marja C. P. Timmermans, Nathan M. Springer, Gary J. Muehlbauer: Mendelian and Non-Mendelian Regulation of Gene Expression in Maize. PLoS Genetics 01/2013; 9(1):e1003202. Selected as an Editors' Choice by MaizeGDB, 02/13 ; Recommended by Faculty 1000

 

13. Qing Li, Xiaohong Yang, Shutu Xu, Ye Cai, Dalong Zhang, Yingjia Han, Lin Li, Zuxin Zhang, Shibin Gao, Jiansheng Li, Jianbing Yan: Genome-wide association studies identified three independent polymorphisms associated with α-tocopherol content in maize kernels. PLoS ONE 01/2012; 7(5):e36807.

 

12. Dianyi Shi, Lin Li, Jiewei Zhang, Panfeng Zhao, Lei Xing, Wenjun Xie, Jianbing Yan, Weiwei Jin: Genome-wide examination of chlorophyll metabolic genes in maize and phylogenetic analysis among different photosynthetic organisms. African Journal of Biotechnology. 01/2011; 10:5559-5562.

 

11. Lin Li, Hui Li, Qing Li, Xiaohong Yang, Debo Zheng, Marilyn Warburton, Yuchao Chai, Pan Zhang, Yuqiu Guo, Jianbing Yan, Jiansheng Li: An 11-bp insertion in Zea mays fatb reduces the palmitic acid content of fatty acids in maize grain. PLoS ONE 01/2011; 6(9):e24699.

 

10. Xiaohong Yang, bullet Shibin, Gao , Shutu Xu, bullet Zuxin, Zhang , Boddupalli M Prasanna, Lin Li, bullet Jiansheng, Li , Jianbing Yan: Characterization of a global germplasm collection and its potential utilization for analysis of complex quantitative traits in maize. Molecular Breeding 28/2011; 4: 511-526.

 

9. Lin Li, Hui Li, JiYing Li, ShuTu Xu, XiaoHong Yang, JianSheng Li, JianBing Yan: A genome-wide survey of maize lipid-related genes: candidate genes mining, digital gene expression profiling and co-location with QTL for maize kernel oil. Science China Life sciences 06/2010; 53(6):690-700.

 

8. Xiaohong Yang, Jianbing Yan, Trushar Shah, Marilyn L Warburton, Qing Li, Lin Li, Yufeng Gao, Yuchao Chai, Zhiyuan Fu, Yi Zhou, Shutu Xu, Guanghong Bai, Yijiang Meng, Yanping Zheng, Jiansheng Li: Genetic analysis and characterization of a new maize association mapping panel for quantitative trait loci dissection. Theoretical and Applied Genetics 03/2010; 121(3):417-31.

 

7. Qing Li, Lin Li, Xiaohong Yang, Marilyn L Warburton, Guanghong Bai, Jingrui Dai, Jiansheng Li, Jianbing Yan: Relationship, evolutionary fate and function of two maize co-orthologs of rice GW2 associated with kernel size and weight. BMC Plant Biology 01/2010; 10:143.

 

6. Lin Li, Qing Li, Libo Wang, Zuxin Zhang, Jiansheng Li, Jianbing Yan: Genetic analysis of QTL affecting recombination frequency in whole genome of maize and rice. Scientia Agricultura Sinica. 01/2009; 42:2262-2270.

 

5. Qing Li, Lin Li, JingRui Dai, JianSheng Li, JianBing Yan: Identification and characterization of CACTA transposable elements capturing gene fragments in maize. Chinese Science Bulletin 01/2009; 54:642-651.

 

4. Hailin, Ma; Xiaohong, Yang; Yuqiu, Guo; Lin, Li, Guanghong, Bai; Jiansheng, Li: Correlation Analysis of Kernel Traits and Oil Concentration in Maize. Crops 2009; 1:11.

 

3. Wenkai Xiao, Jing Zhao, Shengci Fan, Lin Li, Jinrui Dai, Mingliang Xu: Mapping of genome-wide resistance gene analogs (RGAs) in maize (Zea mays L.). Theoretical and Applied Genetics 09/2007; 115(4):501-8.

 

2. Gui-Xiang Wang, Yu Chen, Jiu-Ran Zhao, Lin Li, Schuyler S. Korban, Feng-Ge Wang, Jian-Sheng Li, Jin-Rui Dai, Ming-Liang Xu: Mapping of defense response gene homologs and their association with resistance loci in maize. Journal of Integrative Plant Biology 01/2007; 11:1580-1598.

 

1. Jian-Bing Yan, Ji-Hua Tang, Yi-Jiang Meng, Xi-Qing Ma, Wen-Tao Teng, Subhash Chander, Lin Li, Jian-Sheng Li: Improving QTL mapping resolution based on genotypic sampling--a case using a RIL population. Acta Genetica Sinica 08/2006; 33(7):617-24.

 

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